Police are searching for two men after a horror crash at Goldfields Way, Thanowring Road

The hunt for the two men who fled the crash near Temora, which saw a woman thrown from a ute and two people airlifted to Canberra Hospital, with a resulting police operation closing down a major stretch of road.

Goldfields Way, between Temora and Barmedman, was shut for six hours as the operation unfolded in the wake of the horror incident just north of Temora in the early hours of the morning.

Paramedics were called to Goldfields Way, near Thanowring Road, around 1am, responding to reports of a single vehicle having rolled. Upon arrival, they discovered two people requiring treatment that would ultimately see them flown from the crash site - in two different helicopters - to Canberra Hospital.

"One was a female in her 20s, who was ejected from the vehicle ... [the other was] a man in his 40s who was trapped for a period of time," the spokesperson said.

A spokesperson for NSW Police said officers have been told a sedan and a utility were travelling north along the Goldfields Way, when the utility left the road and rolled several times.

A female passenger in the backseat of the ute, aged 24, was ejected, while the male front seat passenger, aged in his 40s, suffered leg and head injuries.

The male drivers of both vehicles fled the scene, police said, with the sedan later found in Temora's Gardiner Street.

IN OTHER NEWS:

Officers from Riverina Police District established a crime scene, which was examined by specialist police from the crash investigation unit.

The 30-kilometre section of road was listed as closed just before 8.30am and was not accessible to non-local traffic until mid-afternoon.

The road remained open to local traffic, however was closed to all other vehicles between the intersection with Thanowring Road, almost opposite Lake Centenary, and Barmedman until it reopened around 2.30pm.

Non-local traffic was diverted along Trungley Hall Road and Mary Gilmore Way for both north and southbound travellers for most of the day.

A NSW Ambulance spokesperson confirmed those left at the crash scene did not sustain life-threatening injuries. Inquiries are under way to locate the two drivers. Anyone with information relating to the incident should contact Crime Stoppers on 1800 333 000.

Our journalists work hard to provide local, up-to-date news to the community. This is how you can continue to access our trusted content: